Summary #

The Goal of troubleshooting LC-MS/MS:

• Isolate the specific, most likely cause of a problem
• Reduce downtime
• Reduce cost
• help service engineer to show up with the correct parts to complete your service quickly

General Troubleshooting guidelines:

• Visual inspection is Key
• Start by “breaking the system down”
• Having a BASELINE for all metrics is critical to proper troubleshooting
   - Logbooks to track problems and solutions
   - Reference values for instrument readbacks
   - System suitability